Synthetic Biology in Precision Medicine and Nanotechnology […]Read More… from Synthetic Biology in Precision Medicine and Nanotechnology
Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury […]Read More… from Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury
Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells […]Read More… from Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells
Pregnancy-associated plasma protein-A drives melanoma metastasis and immune evasion via IGF signaling […]Read More… from Pregnancy-associated plasma protein-A drives melanoma metastasis and immune evasion via IGF signaling
Ubiquitin-Specific Protease 43 Promotes Degradation of Phenylalanine Hydroxylase in Mammalian Cells […]Read More… from Ubiquitin-Specific Protease 43 Promotes Degradation of Phenylalanine Hydroxylase in Mammalian Cells
Role of cytokine-induced plasticity in melanoma on invasive, therapy-resistant cells that express EMT-related genes and pathways […]Read More… from Role of cytokine-induced plasticity in melanoma on invasive, therapy-resistant cells that express EMT-related genes and pathways
SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis […]Read More… from SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis
Interplay Between Immune Checkpoint Modulators and the Epithelial-to-Mesenchymal Transition Axis in Clear Cell Renal Cell Carcinoma […]Read More… from Interplay Between Immune Checkpoint Modulators and the Epithelial-to-Mesenchymal Transition Axis in Clear Cell Renal Cell Carcinoma
Nanotechnology in the Generation and Analysis of Single Cells […]Read More… from Nanotechnology in the Generation and Analysis of Single Cells
Recent Developments in Single-Cell Transcriptomics […]Read More… from Recent Developments in Single-Cell Transcriptomics
Epithelial-to-mesenchymal transition as a robust biomarker and a novel strategy to enhance response to immune checkpoint blockade and targeted therapy in patients with metastatic renal cell carcinoma […]Read More… from Epithelial-to-mesenchymal transition as a robust biomarker and a novel strategy to enhance response to immune checkpoint blockade and targeted therapy in patients with metastatic renal cell carcinoma
Thrombospondin-1 is a targetable marker of invasive, mesenchymal-like melanoma cells […]Read More… from Thrombospondin-1 is a targetable marker of invasive, mesenchymal-like melanoma cells
Effects of epithelial-to-mesenchymal transition on T cell targeting of melanoma cells […]Read More… from Effects of epithelial-to-mesenchymal transition on T cell targeting of melanoma cells
Thrombospondin-1 promotes an aggressive phenotype through epithelial-to mesenchymal transition in human melanoma […]Read More… from Thrombospondin-1 promotes an aggressive phenotype through epithelial-to mesenchymal transition in human melanoma
Epithelial-to-mesenchymal transition as a potential target for antineoplastic therapies. […]Read More… from Epithelial-to-mesenchymal transition as a potential target for antineoplastic therapies.
PAPP-A is a marker of aggressive breast cancer and promotes cancer progression in-vitro […]Read More… from PAPP-A is a marker of aggressive breast cancer and promotes cancer progression in-vitro
Immune checkpoint inhibitors and tumor mutation burden as predictive biomarkers in hepatocellular carcinoma […]Read More… from Immune checkpoint inhibitors and tumor mutation burden as predictive biomarkers in hepatocellular carcinoma
Exosome-based liquid biopsy in the management of hepatocellular carcinoma […]Read More… from Exosome-based liquid biopsy in the management of hepatocellular carcinoma
Thrombospondin 1 promotes anin vitroandin vivoinvasive phenotype through epithelial-to-mesenchymal transition in human melanoma […]Read More… from Thrombospondin 1 promotes anin vitroandin vivoinvasive phenotype through epithelial-to-mesenchymal transition in human melanoma
Juxtamembrane Mimic Peptide Loaded Injectable Sodium Alginate/Bioglass Bioactive Hydrogel for Suppressing Tumor Recurrence in Post-Breast-Conserving-Surgery Treatment […]Read More… from Juxtamembrane Mimic Peptide Loaded Injectable Sodium Alginate/Bioglass Bioactive Hydrogel for Suppressing Tumor Recurrence in Post-Breast-Conserving-Surgery Treatment
Snail and slug as central mediators of the TGF-beta-induced epithelial-to-mesenchymal transition (EMT) in pulmonary fibrosis […]Read More… from Snail and slug as central mediators of the TGF-beta-induced epithelial-to-mesenchymal transition (EMT) in pulmonary fibrosis
Snail and Slug are Key Mediators of TGF-beta-induced Epithelial-to-Mesenchymal Transition in Lung Fibrosis […]Read More… from Snail and Slug are Key Mediators of TGF-beta-induced Epithelial-to-Mesenchymal Transition in Lung Fibrosis
SNAI transcription factors in epithelial-to-mesenchymal transition: Comparative analysis of experimental and idiopathic pulmonary fibrosis […]Read More… from SNAI transcription factors in epithelial-to-mesenchymal transition: Comparative analysis of experimental and idiopathic pulmonary fibrosis
Protein profiling of cultured primary alveolar epithelial type II cells reveals a rapid loss of the alveolar phenotype […]Read More… from Protein profiling of cultured primary alveolar epithelial type II cells reveals a rapid loss of the alveolar phenotype
Rapid loss of the alveolar epithelial cell phenotype during primary culture in a matrix-independent fashion […]Read More… from Rapid loss of the alveolar epithelial cell phenotype during primary culture in a matrix-independent fashion
Mechanism of IGF induced epithelial-to-mesenchymal transition (EMT) in melanoma progression […]Read More… from Mechanism of IGF induced epithelial-to-mesenchymal transition (EMT) in melanoma progression
Metalloproteinase pregnancy associated plasma protein-A (PAPP-A) promotes melanoma progression in vitro […]Read More… from Metalloproteinase pregnancy associated plasma protein-A (PAPP-A) promotes melanoma progression in vitro
Slow-Cycling Melanoma Cells are Resistant to Therapy and Exhibit a Targetable EMT-Related Expression Profile […]Read More… from Slow-Cycling Melanoma Cells are Resistant to Therapy and Exhibit a Targetable EMT-Related Expression Profile
Immune checkpoint blockade therapies for HCC: current status and future implications […]Read More… from Immune checkpoint blockade therapies for HCC: current status and future implications
In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe […]Read More… from In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe
Characterizing and combating the immune modulatory and epithelial-to-mesenchymal plasticity properties of hepatocellular carcinoma-derived cancer stem cells […]Read More… from Characterizing and combating the immune modulatory and epithelial-to-mesenchymal plasticity properties of hepatocellular carcinoma-derived cancer stem cells
Genetic evidence for the role of ultraviolet radiation in the pathogenesis of uveal melanoma […]Read More… from Genetic evidence for the role of ultraviolet radiation in the pathogenesis of uveal melanoma
Gene therapy targeting of choroidal disease and AAV transcytosis through the outer blood retina barrier epithelium […]Read More… from Gene therapy targeting of choroidal disease and AAV transcytosis through the outer blood retina barrier epithelium
Evaluation of tumor specific promoters for transcriptional targeting of hepatocellular carcinoma […]Read More… from Evaluation of tumor specific promoters for transcriptional targeting of hepatocellular carcinoma
Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma […]Read More… from Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma
H-Ferritin and iron activate inflammatory pathways in adipocytes […]Read More… from H-Ferritin and iron activate inflammatory pathways in adipocytes
Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury […]Read More… from Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury
CD73 and PD-L1 as Potential Therapeutic Targets in Gallbladder Cancer […]Read More… from CD73 and PD-L1 as Potential Therapeutic Targets in Gallbladder Cancer
Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity. […]Read More… from Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity.
Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer. […]Read More… from Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer.
Seek and destroy: targeted adeno-associated viruses for gene delivery to hepatocellular carcinoma. […]Read More… from Seek and destroy: targeted adeno-associated viruses for gene delivery to hepatocellular carcinoma.
Evaluation of the Glypican 3 promoter for transcriptional targeting of hepatocellular carcinoma. […]Read More… from Evaluation of the Glypican 3 promoter for transcriptional targeting of hepatocellular carcinoma.
Monitoring Immune Checkpoint Regulators as Predictive Biomarkers in Hepatocellular Carcinoma. […]Read More… from Monitoring Immune Checkpoint Regulators as Predictive Biomarkers in Hepatocellular Carcinoma.
Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma. […]Read More… from Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma.
TNF‑α‑mediated epithelial‑to‑mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma. […]Read More… from TNF‑α‑mediated epithelial‑to‑mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma.
Immune checkpoint molecules are regulated by transforming growth factor (TGF)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma. […]Read More… from Immune checkpoint molecules are regulated by transforming growth factor (TGF)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma.
Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to Sorafenib treatment. […]Read More… from Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to Sorafenib treatment.
Epithelial-to-Mesenchymal Transition: A Mediator of Sorafenib Resistance in Advanced Hepatocellular Carcinoma. […]Read More… from Epithelial-to-Mesenchymal Transition: A Mediator of Sorafenib Resistance in Advanced Hepatocellular Carcinoma.
The role of pregnancy associated plasma protein-A in triple negative breast cancer: a promising target for achieving clinical benefits […]Read More… from The role of pregnancy associated plasma protein-A in triple negative breast cancer: a promising target for achieving clinical benefits
In Vitro and In Silico Analysis of Epithelial-Mesenchymal Transition and Cancer Stemness as Prognostic Markers of Clear Cell Renal Cell Carcinoma. […]Read More… from In Vitro and In Silico Analysis of Epithelial-Mesenchymal Transition and Cancer Stemness as Prognostic Markers of Clear Cell Renal Cell Carcinoma.
Effect of pregnant sera and a pregnancy-associated metalloproteinase (PAPP-A) on melanoma in vitro and in vivo: Insights into melanoma progression during pregnancy and potential new therapeutic targets. […]Read More… from Effect of pregnant sera and a pregnancy-associated metalloproteinase (PAPP-A) on melanoma in vitro and in vivo: Insights into melanoma progression during pregnancy and potential new therapeutic targets.
Embryonic chicken transplantation is a promising model for studying the invasive behavior of melanoma cells […]Read More… from Embryonic chicken transplantation is a promising model for studying the invasive behavior of melanoma cells
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells […]Read More… from Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells
Identifying and targeting determinants of melanoma cellular invasion […]Read More… from Identifying and targeting determinants of melanoma cellular invasion
Aberrant pregnancy-associated plasma protein-A expression in breast cancers prognosticates clinical outcomes […]Read More… from Aberrant pregnancy-associated plasma protein-A expression in breast cancers prognosticates clinical outcomes
Crosstalk between Immune Checkpoint Modulators, Metabolic Reprogramming and Cellular Plasticity in Triple-Negative Breast Cancer […]Read More… from Crosstalk between Immune Checkpoint Modulators, Metabolic Reprogramming and Cellular Plasticity in Triple-Negative Breast Cancer
Advances in CRISPR/Cas systems-based cell and gene therapy […]Read More… from Advances in CRISPR/Cas systems-based cell and gene therapy
TNF-α promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma […]Read More… from TNF-α promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma
Combination targeting of epithelial-to-mesenchymal transition and immune checkpoint molecules resensitizes hepatocellular carcinoma to sorafenib treatment […]Read More… from Combination targeting of epithelial-to-mesenchymal transition and immune checkpoint molecules resensitizes hepatocellular carcinoma to sorafenib treatment
Single-cell RNA sequence analysis reveals USP32 as a therapeutic target to mitigate PD-L1-driven colorectal tumorigenesis in vitro and in vivo […]Read More… from Single-cell RNA sequence analysis reveals USP32 as a therapeutic target to mitigate PD-L1-driven colorectal tumorigenesis in vitro and in vivo
Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review […]Read More… from Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review
Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells […]Read More… from Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells
Impact of Ligand Concentration on the Properties of Nucleic-Acid-Encapsulated MOFs and Inflammation Modulation in Prostate Cancer Cells […]Read More… from Impact of Ligand Concentration on the Properties of Nucleic-Acid-Encapsulated MOFs and Inflammation Modulation in Prostate Cancer Cells
Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation […]Read More… from Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation
Recent progress in CRISPR/Cas9 system for eye disorders […]Read More… from Recent progress in CRISPR/Cas9 system for eye disorders
Advances in applications of the CRISPR/Cas9 system for respiratory diseases […]Read More… from Advances in applications of the CRISPR/Cas9 system for respiratory diseases
Prognostic Role of Immune Checkpoint Regulators in Cholangiocarcinoma: A Pilot Study […]Read More… from Prognostic Role of Immune Checkpoint Regulators in Cholangiocarcinoma: A Pilot Study
Microgel-based bioink for extrusion-based 3D bioprinting and its applications in tissue engineering […]Read More… from Microgel-based bioink for extrusion-based 3D bioprinting and its applications in tissue engineering
Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. […]Read More… from Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice.
Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis. […]Read More… from Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis.
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. […]Read More… from FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis.
Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion. […]Read More… from Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion.
Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. […]Read More… from Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma. […]Read More… from Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma.
Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. […]Read More… from Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury.
Associate Professor Aparna JayachandranAssociate Professor Aparna Jayachandran
Associate Professor Aparna Jayachandran