Immunology

This research is focused in empowering the immune system to fight disease, and in particular cancer. We are undertaking studies on the immunology of cancer and the role of T cell subsets, NKT cells, MAIT (mucosal associated invariant T) cells and gamma-delta T cells. It is hypothesized that defects in the immune system may predispose […]

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Ovarian Cancer

Every 11 hours one woman dies of ovarian cancer in Australia. Approximately 1400 Australia women are diagnosed with the cancer each year, and nearly 800 die annually, making ovarian cancer the fourth most common cause of cancer-related death in women in Australia. The high mortality rate in ovarian cancer patients results from the diagnosis of […]

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Chronic Lymphoctic Leukemia (CLL)

CLL is the most common type of leukemia in adults in the Western world. There is evidence that genetic components contribute to the aetiology of CLL, but no definitive susceptibility genes have been identified. This project is studying the role of immune cells in the regulation of disease progression. The Institute is in a unique […]

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Langerhans Cell Histocytosis

A major field of our research is directed towards understanding the basic biology of histiocytic diseases. We have been studying a human form of histiocytosis called Langerhans cell histiocytosis (LCH) for many years. In this disease, cells called Langerhans cells accumulate in various tissues to form cancer-like lesions. The causes and mechanisms controlling the development […]

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