The role of STAT3 signaling in mediating tumor resistance to cancer therapy […]Read More… from The role of STAT3 signaling in mediating tumor resistance to cancer therapy
Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478 […]Read More… from Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478
The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR […]Read More… from The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR
The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression […]Read More… from The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity […]Read More… from Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity
Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells […]Read More… from Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells
Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab […]Read More… from Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab
Antibodies specifically targeting a locally misfolded region of tumor associated EGFR […]Read More… from Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib […]Read More… from Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib
Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation […]Read More… from Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation
Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo […]Read More… from Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity […]Read More… from Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity
Expression of the adaptor protein Tks5 in human cancer: prognostic potential […]Read More… from Expression of the adaptor protein Tks5 in human cancer: prognostic potential
Monoclonal Antibody 806 Inhibits the Growth of Tumor Xenografts Expressing either the de2-7 or Amplified Epidermal Growth Factor Receptor (EGFR) but not Wild-Type EGFR […]Read More… from Monoclonal Antibody 806 Inhibits the Growth of Tumor Xenografts Expressing either the de2-7 or Amplified Epidermal Growth Factor Receptor (EGFR) but not Wild-Type EGFR
Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity […]Read More… from Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity
SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor […]Read More… from SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor
Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth […]Read More… from Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth
STAT3 signaling mediates tumour resistance to EGFR targeted therapeutics […]Read More… from STAT3 signaling mediates tumour resistance to EGFR targeted therapeutics
Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics […]Read More… from Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics
Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies […]Read More… from Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies
Potent and Selective Cytotoxic and Anti-inflammatory Gold(III) Compounds Containing Cyclometalated Phosphine Sulfide Ligands […]Read More… from Potent and Selective Cytotoxic and Anti-inflammatory Gold(III) Compounds Containing Cyclometalated Phosphine Sulfide Ligands
Antitumor and Antiangiogenic Properties of Gold(III) Complexes Containing Cycloaurated Triphenylphosphine Sulfide Ligands […]Read More… from Antitumor and Antiangiogenic Properties of Gold(III) Complexes Containing Cycloaurated Triphenylphosphine Sulfide Ligands
Cortical tension initiates the positive feedback loop between cadherin and F-actin […]Read More… from Cortical tension initiates the positive feedback loop between cadherin and F-actin
Recent Developments in Single-Cell Transcriptomics […]Read More… from Recent Developments in Single-Cell Transcriptomics
Dynamics of transforming growth factor β signaling and therapeutic efficacy […]Read More… from Dynamics of transforming growth factor β signaling and therapeutic efficacy
Direct integrin avb6-Erk binding: implications for tumour growth […]Read More… from Direct integrin avb6-Erk binding: implications for tumour growth
The avb6 integrin regulates its own expression with cell crowding: implications for tumor progression. […]Read More… from The avb6 integrin regulates its own expression with cell crowding: implications for tumor progression.
Distinct regulation of glucose transport by Interleukin-3 and oncogenes in a murine bone marrow derived cell line […]Read More… from Distinct regulation of glucose transport by Interleukin-3 and oncogenes in a murine bone marrow derived cell line
N -glycosylation of glucose transporter-1 (Glut-1) is associated with increased transporter affinity for glucose in human leukemic cells […]Read More… from N -glycosylation of glucose transporter-1 (Glut-1) is associated with increased transporter affinity for glucose in human leukemic cells
IL-3 induces apoptosis: Differential effect of IL-3 on the survival and growth response of parental and oncogene-transfected cells […]Read More… from IL-3 induces apoptosis: Differential effect of IL-3 on the survival and growth response of parental and oncogene-transfected cells
Telomerase activity in a specific cell subset coexpressing integrin b1/EGFR but not p75NGFR/bcl2 in normal human epithelial cell. […]Read More… from Telomerase activity in a specific cell subset coexpressing integrin b1/EGFR but not p75NGFR/bcl2 in normal human epithelial cell.
Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 activity for glucose is enhanced during the respiratory burst. […]Read More… from Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 activity for glucose is enhanced during the respiratory burst.
Regulation of glucose transport by interleukin-3 in growth factor-dependent and oncogene-transformed bone marrow derived cell lines. […]Read More… from Regulation of glucose transport by interleukin-3 in growth factor-dependent and oncogene-transformed bone marrow derived cell lines.
The impact of low dose carcinogens and environmental disrupters on tissue invasion and metastasis. […]Read More… from The impact of low dose carcinogens and environmental disrupters on tissue invasion and metastasis.
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. […]Read More… from FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis.
Phase Characterization and Bioactivity Evaluation of Nucleic Acid-Encapsulated Biomimetically Mineralized ZIF-8 […]Read More… from Phase Characterization and Bioactivity Evaluation of Nucleic Acid-Encapsulated Biomimetically Mineralized ZIF-8
Targeting telomerase utilizing zeolitic imidazole frameworks as non-viral gene delivery agents across different cancer cell types […]Read More… from Targeting telomerase utilizing zeolitic imidazole frameworks as non-viral gene delivery agents across different cancer cell types
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. […]Read More… from Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.
A New Era of Integration between Multiomics and Spatio-Temporal Analysis for the Translation of EMT towards Clinical Applications in Cancer […]Read More… from A New Era of Integration between Multiomics and Spatio-Temporal Analysis for the Translation of EMT towards Clinical Applications in Cancer
Identification of a cell surface protein with a role in stimulating human keratinocyte proliferation, expressed during development and carcinogenesis […]Read More… from Identification of a cell surface protein with a role in stimulating human keratinocyte proliferation, expressed during development and carcinogenesis
PTHrP and cell division: expression and localization of PTHrP in a keratinocyte cell line (HaCaT) during the cell cycle […]Read More… from PTHrP and cell division: expression and localization of PTHrP in a keratinocyte cell line (HaCaT) during the cell cycle
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport […]Read More… from Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1 […]Read More… from Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1
Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework‐8 (ZIF‐8) […]Read More… from Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework‐8 (ZIF‐8)
Modulation of metal-azolate frameworks for the tunable release of encapsulated glycosaminoglycans […]Read More… from Modulation of metal-azolate frameworks for the tunable release of encapsulated glycosaminoglycans
Functionalization of elongated tetrahexahedral Au nanoparticles and their antimicrobial activity assay […]Read More… from Functionalization of elongated tetrahexahedral Au nanoparticles and their antimicrobial activity assay
Multimodal Imaging and Soft X‐Ray Tomography of Fluorescent Nanodiamonds in Cancer Cells […]Read More… from Multimodal Imaging and Soft X‐Ray Tomography of Fluorescent Nanodiamonds in Cancer Cells
A Novel Gene Delivery Approach Using Metal Organic Frameworks in Human Islet-Derived Progenitor Cells […]Read More… from A Novel Gene Delivery Approach Using Metal Organic Frameworks in Human Islet-Derived Progenitor Cells
ZIF-C as non-viral delivery system for CRISPR/Cas9 mediated hTERT knockdown in cancer cells […]Read More… from ZIF-C as non-viral delivery system for CRISPR/Cas9 mediated hTERT knockdown in cancer cells
Cancer Biology / MechanismsCancer Biology / Mechanisms
Cancer Biology / Mechanisms